You can replace the pickups fine, however diff guitars have diff wiring schemes for pickups, like coil tap etc etc, so you need to have some handy schematics before you begin, and ofcourse knowledge of soldering and a little bit of an idea about pots, capacitors, resistors would help in your journey......
Guitars - Epiphone Les Paul Standard Plain Top, GB&A Strat, Yamaha C70
Amp - Laney Cub 10 (FOR SALE), Blackheart Little Giant Head, 1X12 Cab (DIY) w/ Eminence Governor Speaker
Pedals - Vox Satchurator, Boss ME-25, EHX LPB-1 - DIY, Marshall Plexi Pedal (DIY), TS-808 (DIY)
**Arya Pedals makes custom pedals just the way you need it, and for a price that does not break your bank**
**Reach out at http://www.facebook.com/AryaPedals or email - aryasridhar(at)gmail.com, or PM me on IGT.**