Not directly to the speakers, since speakers expect a line level signal and your guitar signal is much lower. You'll need a preamp in between. OR, you could feed the input signal to a computer, and output of the PC to the speakers. Fiddle with the Windows volume control settings and you are bound to get a tone out of it.
After that, welcome to the world of guitar-PC-nerd-geeks!
My gear, currently up for sale
Washburn X-16 anarchy - SOLD!!
duncan pickups - I wonder why Im selling these.